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Cirrhosis: Beta-Blockers for Portal Hypertension and Varices

Overview

Beta-blocker medicines are used to prevent an episode of variceal bleeding by lowering the pressure in the enlarged veins (varices). Variceal bleeding occurs when the pressure increases in the portal vein system and the veins in the esophagus, stomach, and rectum enlarge to help blood flow through the liver.

By slowing the heart rate and widening the blood vessels, beta-blocker medicines such as propranolol and nadolol appear to lower the pressure in varices that bypass the liver. In people who have esophageal varices, beta-blockers have been shown to reduce the risk of having a first episode of bleeding. They also reduce risk in people who have had a variceal bleed. They are usually prescribed for people who have moderate-to-large varices.

Credits

Current as of: October 19, 2023

Author: Healthwise Staff
Clinical Review Board
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This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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